The Oligonucleotide Therapeutics Society Presents the 2021 Virtual Conference

OTS 2021 Virtual Conference

SAN DIEGO, Sept. 04, 2021 (GLOBE NEWSWIRE) — The Oligo Meeting is purposefully designed to bring people together to share incredible advancements in the field of oligonucleotide therapeutics. While still unable to come together in person, OTS leadership believes in the power of sharing science and the dedicated organizing committee has planned a professional, outstanding, and exciting event in which attendees will join leading scientists from around the world.

Last year’s virtual meeting was extraordinarily successful, and this year’s virtual conference has been carefully planned to be even more seamlessly engaging and productive. All the components of the in-person annual meeting will be included: sessions, short talks, posters, exhibitors, and networking, which will be accessed through one online platform. Recorded talks and posters can be viewed on-demand through December 31, 2021, for all registered delegates. A fun and interactive networking tool will be available throughout the entire four days of the meeting, 24 hours a day.

Session topics feature Nucleic Acid Chemistry, Rare Diseases, 20th Anniversary of Mammalian RNAi, Delivery, Genome and RNA Editing, Bob Letsinger, PhD – 100 Years of History, and the Awards Presentation. The final sessions include two Oligonucleotide Preclinical sessions and finish with the highly anticipated Clinical Studies session.

This year’s featured event speakers include an outstanding lineup of leading experts covering a broad range of oligonucleotide-based disciplines.

Stanley T. Crooke, MD, PhD, Founder and CEO of n-Lorem Foundation and founder, former CEO, and Chairman of the Board at Ionis led the scientific development of a new platform for drug discovery: antisense technology. He engineered the creation of one of the largest, more advanced development pipelines in the biotechnology industry.

John Maraganore, PhD, is the CEO and Director of Alnylam Pharmaceuticals, which has led the translation of RNA interference from Nobel Prize-winning discovery into an innovative, entirely new class of medicines.

Marie Wikström Lindholm, PhD, SVP and Head of Molecular Design at Silence Therapeutics built and leads a skilled team at Silence focusing on fine-tuning the design of their proprietary GalNAc-conjugated siRNA technology and exploring siRNA delivery outside the hepatocyte.

Craig Mello, PhD, is a joint winner of the 2006 Nobel Prize in Physiology or Medicine for the discovery of RNA interference. He has been involved in several RNAi-based biotechnology companies and recently co-founded Atalanta Therapeutics.

Kelvin K. Ogilvie, PhD, a leading expert on biotechnology, bioorganic chemistry, and genetic engineering, invented the drug Ganciclovir and developed a general method for the chemical synthesis of large RNA molecules, which is still the basis for RNA synthesis worldwide.

Laura Sepp-Lorenzino, PhD oversees all drug research across in vivo and engineered cell therapy areas as Chief Scientific Officer at Intellia Therapeutics, Inc., a company developing curative genome editing treatments to positively transform the lives of people with genetic diseases.

These are just a few of the many experts that attendees will hear from as they present interesting and cutting-edge topics. Last year’s virtual conference received rave reviews from participants and this year’s virtual meeting is expected to be even more spectacular.

Those wishing to attend can register here.

Media Contact:

Geri Beaty

Phone: (619)795-9458

Email: info@oligotherapeutics.org

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OTS 2021 Virtual Conference

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OKEx เร่งการนำ NFT ไปใช้ด้วย DeFi Hub, NFT Marketplace

OKEx ยังคงมุ่งมั่นต่อการพัฒนาอุตสาหกรรมคริปโตและการเงินแบบไร้ศูนย์กลางด้วยการเปิดตัว DeFi Hub

วิคตอเรีย, เซเชลส์, Sept. 04, 2021 (GLOBE NEWSWIRE) — OKEx (www.okex.com) จุดแลกเปลี่ยนสกุลเงินคริปโตเคอเรนซี่และอนุพันธ์ชั้นนำระดับโลก วันนี้ได้ประกาศเปิดตัว DeFi Hub ระบบนิเวศสินทรัพย์ดิจิทัลแบบไร้ศูนย์กลาง ปัจจุบันแพลตฟอร์มนี้มีผลิตภัณฑ์หลัก 2 รายการ ได้แก่: NFT Marketplace และ DeFi Dashboard

NFT Marketplace นั้นเป็นแพลตฟอร์ม NFT แบบ End-to-End ที่สร้างขึ้นเพื่อช่วยส่งเสริมผู้สร้างและสร้างแรงบันดาลใจให้นักสะสม ทุกคนสามารถซื้อ ขาย และแลกเปลี่ยน NFT ได้โดยตรงผ่านแพลตฟอร์มนี้ โดยไม่ต้องจ่ายค่าธรรมเนียมให้ OKEx สิ่งที่ทำให้ NFT Marketplace ความโดดเด่นกว่าก็คือ ทุกคนสามารถใช้แพลตฟอร์มนี้เพื่อสร้าง NFT ของตนเองได้ทุกประเภท โดยใช้บล็อกเชน OEC หรือ Ethereum

จะสามารถซื้อ NFT ที่สร้างขึ้นใหม่ได้บน NFT Marketplace และผู้สร้างจะได้รับความยืดหยุ่นในการตั้งค่าค่าลิขสิทธิ์ของตนเอง ซึ่งแสดงให้เห็นถึงความมุ่งมั่นของ OKEx ในการปกป้องผลประโยชน์ของผู้สร้าง โดยที่ผู้สร้างจะได้รับค่าสิทธิสำหรับทุกธุรกรรมหลังจากนั้นในตลาดรองของ NFT Marketplace นอกจากนี้ NFT Marketplace ยังช่วยให้ผู้ใช้สามารถนำเข้า NFT ที่ถูกสร้างขึ้นบนแพลตฟอร์มอื่นๆ ที่รองรับ

DeFi Hub ยังเสนอวิธีการดูและจัดการสินทรัพย์แบบไร้ศูนย์กลางทั่วเครือข่ายบล็อกเชนหลักและโปรโตคอล DeFi DeFi Dashboard จะแสดงทั้งมุมมองพอร์ตการลงทุนทั้งหมด ตลอดจนมุมมองแยกต่างหากสำหรับของดิจิทัลที่สะสมได้

“ตลาด NFT กำลังได้รับความนิยมเพิ่มขึ้นอย่างรวดเร็ว ทำให้เกิดความต้องการระบบที่ครอบคลุมสำหรับการจัดการ NFT” Lennix Lai ผู้อำนวยการ OKEx กล่าวในแถลงการณ์ เขาได้กล่าวต่อ:

“DeFi Hub ได้ช่วยเราในการสร้าง NFT Marketplace ที่จะเร่งการนำ NFT ไปใช้โดยทำให้ทุกคนสามารถสร้าง แลกเปลี่ยน และขาย NFT ได้ง่ายกว่าที่เคย เรายังรู้สึกตื่นเต้นที่จะเปิดตัว DeFi Dashboard เพื่อนำเสนอการปรับปรุงที่จำเป็นอย่างมากด้านการแสดงภาพพอร์ตลงทุนคริปโตเคอเรนซี่ต่อผู้ใช้

เกี่ยวกับ OKEx

OKEx ก่อตั้งขึ้นในปี 2017 เป็นหนึ่งในจุดแลกเปลี่ยนสกุลเงินคริปโตเคอเรนซี่และอนุพันธ์ชั้นนำของโลก OKEx ได้นำเทคโนโลยีบล็อกเชนมาใช้ในเชิงนวัตกรรม เพื่อเปลี่ยนโฉมระบบนิเวศทางการเงิน และนำเสนอผลิตภัณฑ์ โซลูชัน และเครื่องมือการซื้อขายที่หลากหลายและซับซ้อนที่สุดในตลาด ผลิตภัณฑ์และบริการคริปโตที่ครอบคลุม ความมุ่งมั่นอย่างแน่วแน่ต่อการสร้างนวัตกรรม และการดำเนินงานในท้องถิ่นเพื่อให้บริการผู้ใช้ได้ดียิ่งขึ้น ทำให้ OKEx มุ่งมั่นที่จะขจัดอุปสรรคทางการเงิน และตระหนักถึงโลกแห่งบริการทางการเงินสำหรับทุกคน

ติดต่อเรา 

Vivien Choi / Andrea Leung

media@okex.com

Floating Dutch Cow Farm Aims to Curb Climate Impact

Among the cranes and containers of the port of Rotterdam is a surreal sight: a herd of cows peacefully feeding on board what calls itself the world’s first floating farm.

In the low-lying Netherlands where land is scarce and climate change is a daily threat, the three-story glass and steel platform aims to show the “future of breeding”.

The buoyant bovines live on the top floor, while their milk is turned into cheese, yogurt and butter on the middle level, and the cheese is matured at the bottom.

“The world is under pressure,” says Minke van Wingerden, 60, who runs the farm with her husband Peter.

“We want the farm to be as durable and self-sufficient as possible.”

The cows are a sharp contrast to the huge ships and the smoke from the refineries of Europe’s biggest seaport, which accounts for 13.5 percent of the country’s emissions.

With their floating farm, which opened in 2019, Peter and Minke say they wanted to “bring the countryside into the town”, boost consumer awareness and create agricultural space.

The Dutch are no strangers to advanced farming methods, using a network of huge greenhouses in particular to become the world’s second biggest agricultural exporter after the United States.

‘Moves with the tide’

The Netherlands is one of Europe’s largest per capita emitters of climate change gases and faces a major problem with agricultural emissions, particularly in the dairy sector which produces large amounts of methane from cows.

Those emissions in turn fuel the rising waters that threaten to swamp the country, a third of which lies below sea-level, and further reduce the land in one of the most densely populated nations on Earth.

The floating farm therefore aims to keep its cows’ feet dry in both the long-term, by being sustainable, and the short-term, by, well, floating.

“We are on the water, so the farm moves with the tide — we rise and fall up to two meters. So in case of flooding, we can continue to produce,” says Minke van Wingerden.

In terms of sustainability, the farm’s cows are fed on a mixture of food including grapes from a foodbank, grain from a local brewery, and grass from local golf courses and from Rotterdam’s famed Feyenoord football club — saving on waste as well as the emissions that would be required to create commercial feed for the animals.

Their manure is turned into garden pellets — a process that helps further cut emissions by reducing methane — and their urine is purified and recycled into drinking water for the cows, whose stable is lined with dozens of solar panels that produce enough electricity for the farm’s needs.

‘Cows don’t get seasick’

The farm is run by a salaried farmer but the red and white cows, from the Dutch-German Meuse-Rhin-Yssel breed, are milked by robots.

The cheeses, yogurts and pellets are sold at a roadside shop alongside fare from local producers.

The products are also sold to restaurants in town by electric vehicles.

“I was immediately seduced by the concept,” says Bram den Braber, 67, one of 40 volunteers at the farm, as he fills bottles of milk behind the counter of the store.

“It’s not blood running through my veins, it’s milk.”

The idea of the farm is also to make farming “more agreeable, interesting and sexy”, and not just to be environmentally friendly, says Minke van Wingerden.

When she and her husband first approached port authorities with the idea to build a floating farm, they said “are you nuts?”, she recalls.

But the farm is set to turn a profit for the first time at the end of 2021, with consumers apparently ready to pay the 1.80 euro ($2.12) a liter for milk produced there, compared to around one euro at a supermarket.

They are also aiming to build a second floating farm to grow vegetables, and to export their idea, with a project already under way in the island nation of Singapore.

Most importantly, while farming goes greener, the animals don’t.

“No, the cows don’t get seasick,” says van Wingerden. “The water moves only a little bit, it’s like you were on a cruise ship.”

Source: Voice of America

Brazil Starts Booster Shots While Many Still Await 2nd Jab

SAN PAULO – Some cities in Brazil are providing booster shots of the COVID-19 vaccine, even though most people have yet to receive their second jabs, in a sign of the concern in the country over the highly contagious delta variant.

Rio de Janeiro, currently Brazil’s epicenter for the variant and home to one of its largest elderly populations, began administering the boosters Wednesday. Northeastern cities Salvador and Sao Luis started on Monday, and the most populous city of Sao Paulo will begin Sept. 6. The rest of the nation will follow the next week.

France, Israel, China and Chile are among those countries giving boosters to some of their older citizens, but more people in those countries are fully vaccinated than the 30% who have gotten two shots in Brazil. A U.S. plan to start delivery of booster shots by Sept. 20 for most Americans is facing complications that could delay third doses for those who received the Moderna vaccine, administration officials said Friday.

About nine out of 10 Brazilians have been vaccinated already or plan to be, according to pollster Datafolha. Most have gotten their first shot but not their second.

Brazil’s cases and deaths have been falling for two months, with 621 deaths reported in the seven days through Sept. 2 — far below April’s peak of more than 3,000 reported deaths over a seven-day period. Older Brazilians have expressed concern about the efficacy of the Chinese Sinovac vaccine against the delta variant, prompting authorities to offer the booster shots.

Diana dos Santos, 71, received two shots of the Sinovac vaccine even after President Jair Bolsonaro spent months publicly criticizing it. Dos Santos, who lives Rio’s low-income Maré neighborhood, is diabetic and was hospitalized for a heart condition. She refuses to leave home until she gets her booster.

“I can’t go out like before and I’m still afraid of all of this,” dos Santos said. “I will feel safer (with a booster).”

Because of the variant, some experts say the government should slow the rollout of boosters and focus on distributing second doses. Delta is the most contagious variant identified, and many studies have suggested that one dose doesn’t protect against it.

Two shots provide strong protection, with nearly all hospitalizations and deaths among the unvaccinated.

Ethel Maciel, an epidemiologist and professor at the Federal University of Espirito Santo, said pushing boosters at this early stage recalls the lack of concern given the gamma variant that overwhelmed Amazonian city Manaus earlier this year, only to feed a new wave nationwide. Brazil has seen more than 580,000 deaths from COVID-19, making it home to world’s eighth-highest toll on a per capita basis.

“It seems we’re in the same movie, repeating the same errors,” Maciel said. “It’s only a matter of time until what’s happening in Rio leads to a greater number of more serious cases in the rest of the country.”

The delta variant already is dominant in Rio de Janeiro state, detected in 86% of the samples collected from COVID-19 patients, according to the Ministry of Science, Technology and Innovation. Intensive care units have reached full capacity in eight municipalities, although only a small rise in deaths have been recorded so far.

Authorities in Sao Paulo state expect a similar scenario within weeks. It registered its first confirmed death from the delta variant on Tuesday, a 74-year-old woman who had received two Sinovac shots.

Globally, doubts have plagued Chinese vaccines, especially as the delta variant has gained hold in many countries. Chinese officials have maintained the vaccine protects against delta, particularly preventing hospitalizations and severe cases.

Still, Brazil’s Health Minister Marcelo Queiroga said Aug. 25 that people aged 70 or older or who have a weak immune system will be eligible for a third dose, starting Sept. 15 — preferably with the Pfizer vaccine. He said that people over 18 will have received their first doses by then, although he didn’t address their vulnerability to the delta variant without a second shot.

He also criticized governors and mayors who sought to deliver booster shots earlier, saying it could lead to vaccine shortages.

Carla Domingues, former coordinator of Brazil’s national immunization program, agrees with the need to provide the elderly boosters, but not for people aged 70 and up right away. Shots should first go to nursing homes and people who are bed-ridden, she said, then people 80 and above, with the age slowly decreasing as supply allows.

“Certainly, there will be problems with shortage, because there won’t be enough vaccine,” Domingues said.

Japan and South Korea both wrestled with slow vaccine rollouts, and under half their populations are fully vaccinated; their governments are only planning booster shots in the fourth quarter of this year. Malaysia also is considering boosters, but Health Minister Khairy Jamaluddin said the priority is those who haven’t received a first dose.

Thailand began giving booster shots even as most people wait to be vaccinated — but only for health and front-line workers who received two Sinovac shots. The decision came after a nurse died of COVID-19 in July.

Russia, Hungary and Serbia also are giving boosters, although there has been a lack of demand in those countries for the initial shots amid abundant supplies.

In addition to doubts over boosters, the issue is sensitive due to implications for global vaccine distribution. World Health Organization Director-General Tedros Adhanom Ghebreyesus has called for a moratorium on boosters “to allow those countries that are furthest behind to catch up.”

Epidemiologist Denise Garrett, vice president of the Sabin Vaccine Institute, which advocates for expanding global vaccine access, said in an interview there is no doubt about the need for two jabs, but she sees no scientific or moral justification for a third.

“Authorities giving a third dose are prioritizing protection against light disease instead of shielding people in poor countries from death,” said Garrett, who is Brazilian. “That is shameful, immoral, and this vaccine inequity must end.”

That doesn’t sway 97-year-old Maria Menezes, who wants to spend time outside her home where she has lived for the last seven decades in Rio’s western region. Her two daughters say Menezes wants to a booster shot.

“She asked us to take her for the third vaccine,” said daughter Cristina França, 38. “It will be important to beef up her immunity to reduce her risks. Her life won’t change much after the third dose, because she is more frail now, but she would live with more calm.”

Source: Voice of America

Coronavirus Can Cause ‘Severe Illness’ in Children, CDC Warns

A U.S. Centers for Disease Control and Prevention report released Friday says the coronavirus can cause “severe illness” in children and adolescents.

From late June to mid-August, when there was an “increased circulation” of the highly contagious delta variant of the coronavirus, weekly COVID-associated hospitalization rates for children and adolescents rose nearly fivefold. Hospitalization rates, however, were “10 times higher among unvaccinated than among fully vaccinated adolescents,” the study said.

India’s health ministry said Saturday morning that 42,618 new COVID cases were reported in the previous 24-hour period and 330 deaths.

India is second only to the United States in COVID tolls. India has almost 33 million COVID-19 infections and 440,225 deaths, according to Johns Hopkins Coronavirus Resource Center. The U.S., Johns Hopkins says, has nearly 40 million infections and close to 650,000 deaths. Public health officials have warned, however, that India’s tolls are likely undercounted.

The COVID-related death of a woman in her 90s is the first COVID-related death in New Zealand in more than 200 days.

In addition to COVID, doctors say the women had several underlying health problems.

Fighter Oscar de la Hoya has been hospitalized with COVID-19, forcing him to drop out of a comeback fight scheduled for next month.

Johns Hopkins Coronavirus Resource Center said early Saturday that it had recorded nearly 219.8 million global COVID infections and 4.5 million deaths. The center said 5.4 billion vaccines have been administered.

Source: Voice of America

Tourists from several countries visited Azerbaijan during COVID-19 pandemic – expert

The tourists from Arab countries, Turkey, and Russia mainly visited Azerbaijan during the COVID-19 pandemic, Azerbaijani expert in the field of tourism Jeyhun Ashirov told Trend on Sept. 3.

“However, citizens from more than 20 countries were allowed to enter the country by planes on August 5,” the expert said. “The recent observations show that tourists from these countries also arrive in Azerbaijan.”

“The citizens from 29 countries can visit Azerbaijan by planes,” Ashirov added.

“Tourists from these countries can come to Azerbaijan by observing the certain quarantine rules,” the expert said. “They are mainly citizens of Arab countries, Turkey and Russia. There are also tourists from other countries, but very few.”

“In general, the trips to Azerbaijan are not massive,” Ashirov said. “About 80 percent of visitors come for tourism purposes. As the tourist season is already coming to an end, the number of incoming tourists from abroad is expected to decrease.”

Currently, citizens of 29 countries are allowed to enter Azerbaijan. The list of these countries is as follows:

– Turkey,

– Russia,

– US,

– Bahrain,

– UAE,

– United Kingdom,

– Israel,

– Hungary,

– Qatar,

– Germany,

– Austria,

– Belgium,

– Czech Republic,

– Denmark,

– Ireland,

– Spain,

– Sweden,

– Switzerland,

– Canada,

– Luxembourg,

– Malta,

– Netherlands,

– Poland,

– Portugal,

– Serbia,

– Singapore,

– Slovenia,

– Slovakia,

– Greece.

Source: TREND News Agency

Iranian currency rates for September 4

The Central Bank of Iran (CBI) has announced the official rate of foreign currencies on September 4, Trend reports referring to CBI.

According to the currency exchange rate of the Central Bank of Iran, 24 currencies have increased and 11 have decreased compared to September 2.

According to CBI, $1 equals 42,000 Iranian rials and 1 euro equals 49,913 rials.

Currency Iranian rial on September 4 Iranian rial on September 2

1 US dollar USD 42,000 42,000

1 British pound GBP 58,224 57,920

1 Swiss franc CHF 45,969 45,932

1 Swedish krona SEK 4,915 4,883

1 Norwegian krone NOK 4,713 4,837

1 Danish krone DKK 6,694 6,694

1 Indian rupee INR 576 576

1 UAE dirham AED 11,437 11,437

1 Kuwaiti dinar KWD 139,711 139,699

100 Pakistani rupees PKR 25,151 25,152

100 Japanese yens JPY 38,305 38,173

1 Hong Kong dollar HKD 5,405 5,402

1 Omani rial OMR 109,231 109,235

1 Canadian dollar CAD 33,538 33,291

1 New Zealand dollar NZD 30,016 29,687

1 South African rand ZAR 2,941 2,919

1 Turkish lira TRY 5,057 5,052

1 Russian ruble RUB 578 576

1 Qatari riyal QAR 11,539 11,539

100 Iraq dinars IQD 2,878 2,879

1 Syrian pound SYP 34 34

1 Australian dollar AUD 31,258 30,948

1 Saudi riyal SAR 11,200 11,201

1 Bahraini dinar BHD 111,703 111,704

1 Singapore dollar SGD 31,300 31,262

100 Bangladeshi takas BDT 49,377 49,292

10 Sri Lankan rupees LKR 2,096 2,106

1 Myanmar kyat MMK 26 26

100 Nepalese rupees NPR 35,785 35,805

1 Libyan dinar LYD 9,308 9,294

1 Chinese yuan CNY 6,509 6,503

100 Thai baths THB 129,297 130,021

1 Malaysian ringgit MYR 10,131 10,112

1,000 South Korean wons KRW 36,344 36,324

1 Jordanian dinar JOD 59,238 59,239

1 euro EUR 49,913 49,776

100 Kazakh tenge KZT 9,872 9,854

1 Georgian lari GEL 13,484 13,506

1,000 Indonesian rupiahs IDR 2,946 2,946

1 Afghan afghani AFN 526 526

1 Belarus ruble BYN 16,699 16,735

1 Azerbaijani manat AZN 24,721 24,721

100 Philippine pesos PHP 84,153 84,097

1 Tajik somoni TJS 3,708 3,697

1 Turkmen manat TMT 11,988 11,988

In Iran, the official exchange rate is used for the import of some essential products.

SANA system is a system introduced by the Central Bank of Iran to the currency exchange offices, where the price of 1 euro is 312,280 rials, and the price of $1 is 262,769 rials.

NIMA is a system intended for the sale of a certain percentage of the foreign currency gained from export.

The price of 1 euro in this system is 274,257 rials, and the price of $1 is 230,774 rials.

In the black market, $1 is worth about 267,000-270,000 rials, while 1 euro is worth about 311,000-314,000 rials.

Source: TREND News Agency